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Slide 1 - Nanoliposomes for Cosmetics
Slide 2 - About Us CD Bioparticles is an established drug delivery company which provides customized solutions for developing and producing new, biocompatible drug delivery systems. CD Bioparticles offers both products and services to support cosmetic formulation development. In cosmetics, since skin is the first defensive barrier against external factors and prevents many substances from entering the underlying layers or systemic circulation, there are some limitations to deliver the active ingredient to the target site. By using liposomes, we are able to overcome some restrictions such as low penetration, solubility, stability, duration of effect and high side effects or costs, and improve some other characteristics. Liposome-encapsulation largely reduces the amount of the active ingredient required for effectiveness as compared to non-encapsulated, pure active ingredients. Today we offer you: We offer fully certified high-quality nanoliposomes for cosmetics. Use FDA GRAS grade materials for high safety. Nanoliposomes have good heat, PH and shear stability and is easy to use. Many types of nanoliposomes encapsulate different natural active substances to match customers' needs. Provide GMP grade nanoliposomes. Immediate and expert scientific support.
Slide 3 - Table of Contents Clipos™ Nanoliposomal Resveratrol ................................................................................... 4 Clipos™ Nanoliposomal THC ................................................................................................5 Clipos™ Nanoliposomal Vitamin A Palmitate ....................................................................6 Clipos™ Nanoliposomal Vitamin C ......................................................................................7 Clipos™ Nanoliposomal Curcumin ......................................................................................8 Clipos™ Nanoliposomal Alpha Lipoic Acid ........................................................................9 Clipos™ Nanoliposomal Vitamins ........................................................................................10 Clipos™ Nanoliposomal Coenzyme Q10 ...........................................................................11 Clipos™ Nanoliposomal Azelaic Acid .................................................................................12 Clipos™ Nanoliposomal Soy Isoflavone ............................................................................13 Clipos™ Nanoliposomal Phenylethyl Resorcinol .............................................................14 Clipos™ Nanoliposomal Vitamin E .....................................................................................15 Clipos™ Nanoliposomal Ferulic Acid .................................................................................16 Clipos™ Nanoliposomal Phytosterol ..................................................................................17 Clipos™ Nanoliposomal Lutein ...........................................................................................18 Clipos™ Nanoliposomal Salicylic Acid ...............................................................................19 Clipos™ Nanoliposomal Retinaldehyde .............................................................................20 Clipos™ Nanoliposomal Sulfur ............................................................................................21 Clipos™ Nanoliposomal Ceramide .....................................................................................22
Slide 4 - 4 www.cd-bioparticles.net Clipos™ Nanoliposomal Resveratrol Catalog no: CDPR-0001 CAS number: 501-36-0 Clipos™ Nanoliposomal Resveratrol has a particle size of less than 30nm and enables the resveratrol to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Resveratrol is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Resveratrol has many targets in the skin, so it can be used as a skincare product to produce whitening, anti- wrinkle, anti-bacteria, anti-inflammation, acne curing and anti-aging effects. It is an emerging natural active substance with high efficiency. Features: Clipos™ Nanoliposomal Resveratrol uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Resveratrol is stable to heat, pH and shearing, so it is convenient to use. Clipos™ Nanoliposomal Resveratrol greatly improves the stability and bioavailability of resveratrol. Clipos™ Nanoliposomal Resveratrol can improve the stability of other active matters in the product and facilitate absorption. Clipos™ Nanoliposomal Resveratrol is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Usage: Add it at room temperature. You may heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should be protected from direct exposure to sunlight (using opaque packaging). It is recommended to add UV absorber to day care products. Storage: Keep it away from light at a temperature below 25°C.
Slide 5 - 5 www.cd-bioparticles.net Clipos™ Nanoliposomal THC Catalog no: CDPR-0002 CAS number: 36062-04-1 Tetrahydrocurcumin (ultra-pure whitening element) is a natural functional whitening ingredient extracted from the roots of Ginger Curcuma longa. Thanks to its potent activity against tyrosinase, the whitening effect of this product is better than that of arbutin; it can effectively inhibit the formation of oxygen free radicals as well as eliminating the formed free radicals. Featured with significant antioxidant effects, such as anti-aging of human skin, skin repair, lightening pigments, and clearing freckles, it is widely applied in various skincare products for whitening, freckle eliminating, and anti-oxidation. Tetrahydrocurcumin is hardly soluble in water while easy to be oxidized and discolored, which limits its application in cosmetics. Clipos™ Nanoliposomal THC has a particle size of less than 30nm and enables tetrahydrocurcumin to be steadily wrapped in nano-carriers, greatly improving the absorption efficiency and bioavailability. This overcomes the original defects and maintains the advantages with a more convenient and wider range of uses. Features: Clipos™ Nanoliposomal THC solves the problem of tetrahydrocurcumin’s tendency to be oxidized and discolored. Clipos™ Nanoliposomal THC uses FDA GRAS materials for safety. Clipos™ Nanoliposomal THC has a good stability towards heat, pH and shearing and is easy to use. Clipos™ Nanoliposomal THC greatly improves the stability and bioavailability of tetrahydrocurcumin. Clipos™ Nanoliposomal THC improves the stability of other actives in the product and promotes absorption. Clipos™ Nanoliposomal THC is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Usage: Add it at room temperature. You may heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should be protected from direct exposure to sunlight (using opaque packaging). It is recommended that UV absorber should be added to day care products. Storage: Keep it away from light at a temperature below 25°C.
Slide 6 - 6 www.cd-bioparticles.net a Clipos™ Nanoliposomal Vitamin A Palmitate Catalog no: CDPR-0003 CAS number: 79-81-2 Clipos™ Nanoliposomal Vitamin A Palmitate has particle size of less than 30nm and enables the Vitamin A to be steadily encapsulated in nanocarriers. Vitamin A palmitate is a vitamin A derivative and a fat-soluble antioxidant. Clipos™ Nanoliposomal Vitamin A Palmitate is water-soluble, transparent, highly effective and non-irritating vitamin A, which can repair cells and protect against UV-induced skin aging, promote the metabolism of epidermis and keratinocytes, and facilitate and strengthen the exfoliation of keratinocytes and the growth of new cells, as well as the production of collagen and elastic fibers, while helping to maintain the normal metabolic cycle of cells. Features: Clipos™ Nanoliposomal Vitamin A Palmitate uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Vitamin A Palmitate is stable to heat, pH and shearing, so it is convenient to use. Clipos™ Nanoliposomal Vitamin A Palmitate is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Clipos™ Nanoliposomal Vitamin A Palmitate greatly improves the stability and bioavailability of vitamin A. Usage: Add it at room temperature. You may heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. Metal ions such as iron ions must be avoided in the system. Better effect with products such as vitamin C and vitamin E. Storage: Keep it away from light at a temperature below 25°C.
Slide 7 - 7 www.cd-bioparticles.net Clipos™ Nanoliposomal Vitamin C Catalog no: CDPR-0004 CAS number: 50-81-7 Clipos™ Nanoliposomal Vitamin C has a particle size of less than 30nm and enables the Vitamin C to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Vitamin C is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Vitamin C is an important antioxidant, involved in multiple reactions in vivo which has functions such as promoting collagen production, blocking melanin synthesis, scavenging free radicals, and preventing skin aging. Features: Clipos™ Nanoliposomal Vitamin C is a non-chemically modified stable L-C nano product that works directly and efficiently without the need of vivo transformation. Clipos™ Nanoliposomal Vitamin C uses GRAS (Recognized Safety) grade materials for safety and non-irritation. Clipos™ Nanoliposomal Vitamin C is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Clipos™ Nanoliposomal Vitamin C greatly improves the stability and bioavailability of vitamin C. Clipos™ Nanoliposomal Vitamin C is stable to heat, pH and shearing, so it is convenient to use. Usage: Add it at ordinary temperature. You may heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. Better effect with products containing vitamin E and ferulic acid. Storage: Keep it away from light at a temperature below 25°C.
Slide 8 - 8 www.cd-bioparticles.net Clipos™ Nanoliposomal Curcumin Catalog no: CDPR-0005 CAS number: 36062-04-1 Clipos™ Nanoliposomal Curcumin has a particle size of less than 30nm and enables the curcumin to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Curcumin is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Curcumin has a variety of biological activities, such as anti-oxidation, anti-infection, anti-inflammatory, anti-coagulation, anti-atherosclerosis and inhibition of tumor growth. The application of curcumin in skincare products has been widely recognized, and has been increasingly applied to whitening, anti-allergy,anti-inflammatory and other products. Features: Clipos™ Nanoliposomal Curcumin uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Curcumin is stable to heat, pH and cuts, so it is convenient to use. Clipos™ Nanoliposomal Curcumin greatly improves the stability and bioavailability of nano-curcumin. Clipos™ Nanoliposomal Curcumin improves the stability and absorption of other actives in the product. Clipos™ Nanoliposomal Curcumin is 100% water soluble and 100% oil soluble (amphiphilic). Usage: Add it at room temperature. You may heat to above 40°C to speed up dissolution rate. Recommended dosage: 1-5%. Storage: Keep it away from light at a temperature below 25°C.
Slide 9 - 9 www.cd-bioparticles.net d Clipos™ Nanoliposomal Alpha Lipoic Acid Catalog no: CDPR-0006 CAS number: 62-46-4 Clipos™ Nanoliposomal Alpha Lipoic Acid has a particle size of less than 30nm and enables the alpha lipoic aci to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Alpha Lipoic Acid is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Alpha lipoic acid is an enzyme existing in mitochondria. Lipoic acid is effective in removing dark eye circles, wrinkles and spots. In addition, it enhances metabolism, improving the body’s blood circulation, so that the skin will no longer be dull and the appearance or pores will be minimized, making your skin enviously firm and delicate. Features: Clipos™ Nanoliposomal Alpha Lipoic Acid uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Alpha Lipoic Acid has good heat, pH and shear stability and is easy to use. Clipos™ Nanoliposomal Alpha Lipoic Acid greatly improves ALA's stability and bioavailability. Clipos™ Nanoliposomal Alpha Lipoic Acid improves the stability and absorption of other actives in the product. Clipos™ Nanoliposomal Alpha Lipoic Acid is 100% water soluble and 100% oil soluble (amphiphilic) for a wide range of applications. Usage: Add it at room temperature. You may heat it to above 40°C to speed up its dissolution, Recommended dosage: 1-3%. Better effect with products containing lipoic acid. Storage: Keep it away from light at a temperature below 25°C.
Slide 10 - 10 www.cd-bioparticles.net Clipos™ Nanoliposomal Vitamins Catalog no: CDPR-0008 CAS number: 79-81-2, 127-47-9, 10191-41-0 Clipos™ Nanoliposomal Vitamin A, E & K is a new multivitamin nanoliposome preparation, designed for anti-aging, eye bags and dark circles. Vitamin A can guarantee the normal state of skin tissue and maintain the normal regeneration of basal cells. Vitamin E is a highly effective antioxidant that protects cell activity. Menaquinone (Vitamin K2) can control blood clotting and significantly reduce the congestion of capillaries in the lower part of the eye. The nano-multivitamin has little incompatibility, with a structure that can be easily combined with water molecules, showing unique advantages in the formulation. Features: Clipos™ Nanoliposomal Vitamins is safe, non-toxic, non-irritating and biodegradable. Clipos™ Nanoliposomal Vitamins does not contain any preservative system. Usage: Add at room temperature, and heating to above 40°C can speed up the dissolution rate. Recommended dosage: 1-5%. Better effects with Nanoliposomal Coenzyme Q10, Nanoliposomal Azelaic Acid, etc. Storage: Recommended to store at 2-8°C
Slide 11 - 11 www.cd-bioparticles.net Clipos™ Nanoliposomal Coenzyme Q10 Catalog no: CDPR-0009 CAS number: 303-98-0 Clipos™ Nanoliposomal Coenzyme Q10 has a particle size of less than 30nm and enables the coenzyme Q10 to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Coenzyme Q10 has stronger antioxidant function, and it can effectively eliminate free radicals and has good anti-aging, anti-wrinkle and whitening functions. Features: Clipos™ Nanoliposomal Coenzyme Q10 uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Coenzyme Q10 has good heat, pH and sheer stability and is easy to use. Clipos™ Nanoliposomal Coenzyme Q10 greatly improves the stability and bioavailability of CoQ10. Clipos™ Nanoliposomal Coenzyme Q10 can improve the stability of other active matters in the product and facilitate absorption. Clipos™ Nanoliposomal Coenzyme Q10 is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Usage: Add it at ordinary temperature. Heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. Better effect with products containing lipoic acid. Storage: Keep it away from light at a temperature below 25°C.
Slide 12 - Clipos™ Nanoliposomal Azelaic Acid Catalog no: CDPR-0010 CAS number: 123-99-9 Clipos™ Nanoliposomal Azelaic Acid has a particle size of less than 30nm and enables the azelaic acid to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. It is a good solution to the deficiency of azelaic acid while maintaining the original advantages. It has good compatibility and is very effective in regulating the normal secretion of sebum, eliminating acne and whitening skin. Azelex, known as azelaic acid, is a natural saturated dicarboxylic acid containing nine carbon atoms and is an important medium-long chain dibasic acid, featured with the effect of inhibiting excessive secretion of grease, eliminating acne and skin whitening, as well as high security. Features: Clipos™ Nanoliposomal Azelaic Acid uses FDA GRAS materials for safety. Clipos™ Nanoliposomal Azelaic Acid is stable to heat, pH and shearing, so it is convenient to use. Clipos™ Nanoliposomal Azelaic Acid overcomes the original shortcomings of azelaic acid while maintaining the advantages and improving bioavailability. Clipos™ Nanoliposomal Azelaic Acid improves the stability of other actives in the product and facilitates absorption. Usage: It allows a wide range of applications, and can be used in various systems such as freshener, essence, cream, and lotions. Add it at room temperature. You may heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. Storage: Keep it away from light at a temperature below 25°C. 12 www.cd-bioparticles.net
Slide 13 - Clipos™ Nanoliposomal Soy Isoflavone Catalog no: CDPR-0011 CAS number: 574-12-9 Clipos™ Nanoliposomal Soy Isoflavone has a particle size of less than 30nm and enables the soy isoflavones to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Nanoliposomal is water-soluble even when it contains an oil-soluble active substance such as soy isoflavone. The solution is completely clear and transparent, so the product is applicable to clear hydrogel formulations. Features: Shearing stability pH stability Heat stability Improvement on skin texture Low viscosity Usage: Recommended dosage: 1% – 3% Storage: Store with its original packaging at room temperature (<25°C). 13 www.cd-bioparticles.net
Slide 14 - Clipos™ Nanoliposomal Phenylethyl Resorcinol Catalog no: CDPR-0012 CAS number: 85-27-8 Clipos™ Nanoliposomal Phenylethyl Resorcinol has a particle size of less than 30nm and enables the phenylethyl resorcinol to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Phenylethyl Resorcinol is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Phenylethyl resorcinol is a new high- efficiency skin whitening agent derived from silver pine. It is clinically proven that its whitening ability is equivalent to that of hydroquinone, approved by various countries and gradually used in cosmetics. Features: Clipos™ Nanoliposomal Phenylethyl Resorcinol uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Phenylethyl Resorcinol greatly improves the stability and bioavailability. Clipos™ Nanoliposomal Phenylethyl Resorcinol can improve the stability of other active matters in the product and facilitate absorption. Usage: Add it at room temperature. Heat it to above 40°C to speed up the dissolution. Recommended dosage: 0.1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should be protected from direct sunlight (using opaque packaging). It is recommended to add UV absorber to day care products. Storage: Keep it away from light at a temperature below 25°C. 14 www.cd-bioparticles.net
Slide 15 - 15 www.cd-bioparticles.net Clipos™ Nanoliposomal Vitamin E Catalog no: CDPR-0013 CAS number: 10191-41-0, 7695-91-2, 59-02-9 Clipos™ Nanoliposomal Vitamin E has a particle size of less than 30nm and enables the vitamin E to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Vitamin E is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Vitamin E can reduce the aging of tissue cells and the production of streak tissue, improve the effect of vitamin A, and prevent the oxidation of vitamin A and vitamin C. The external use of vitamin E has been proven to be effective in supplying vitamin E to the skin. Features: Clipos™ Nanoliposomal Vitamin E is 100% water soluble and 100% oil soluble (amphiphilic) for a wide range of application. Clipos™ Nanoliposomal Vitamin E greatly improves the stability and bioavailability of vitamin E. Clipos™ Nanoliposomal Vitamin E has good heat, pH and shear stability and is easy to use. Clipos™ Nanoliposomal Vitamin E is rich in active substances, which can be up to 20%. Clipos™ Nanoliposomal Vitamin E uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Vitamin E can increase the amount of vitamin E infiltrated into the depth of the epidermis while traditional oil-in-water emulsion loose vitamin E can only stay on the skin surface. Usage: Add it at room temperature. You may heat it to above 40°C to speed up the dissolution. Recommended dosage: 1-5%. Better effect with products containing Nanoliposomal Coenzyme Q10. Storage: Recommended to store it at 2-8°C
Slide 16 - Clipos™ Nanoliposomal Ferulic Acid Catalog no: CDPR-0014 CAS number: 1135-24-6 Clipos™ Nanoliposomal Ferulic Acid has a particle size of less than 30nm and enables the ferulic acid to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Vitamin E is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Ferulic acid is an intercellular adhesive that binds the polysaccharides among cells to make the skin firm and elastic. It is effective in eliminating free radicals, anti-thrombus, anti-bacteria, anti-inflammation, inhibiting tumor, preventing hypertension, and heart diseases, enhancing the vitality of sperm as well as other health functions and protecting the skin. Features: Clipos™ Nanoliposomal Ferulic Acid uses FDA GRAS (Generally Recognized as Safe) materials so it is safe. Clipos™ Nanoliposomal Ferulic Acid has a good stability towards heat, pH and shearing, so it is easy to use. Clipos™ Nanoliposomal Ferulic Acid greatly improves the stability and bioavailability of ferulic acid. Clipos™ Nanoliposomal Ferulic Acid improves the stability and absorption of other actives in the product. Clipos™ Nanoliposomal Ferulic Acid is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses. Usage: Add this product at room temperature and heat it to above 40°C to speed up its dissolution. Recommended dosage: 1-5%. It works better with products such as Nanoliposomal Vitamin C and E. Storage: Keep it away from light at a temperature below 25°C. 16 www.cd-bioparticles.net
Slide 17 - Clipos™ Nanoliposomal Phytosterol Catalog no: CDPR-0015 CAS number: 68441-03-2 Clipos™ Nanoliposomal Phytosterol has a particle size of less than 30nm and enables the phytosterol to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Phytosterol is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Phytosterol is a kind of natural physiologically active substances beneficial to humans. It can inhibit the cholesterol absorption of humans, promote the degradation and metabolism of cholesterol, inhibit the biosynthesis of cholesterol, etc., and has been found to have the function of inhibiting cardiovascular diseases in animal studies. Also, it is effective in anti-cancer, anti-tumor, anti-inflammatory, improving immunity, regulating growth, anti-virus, anti-oxidation, etc. Usage: Add it at room temperature. You may heat it to above 40°C to speed up its dissolution; recommended dosage: 1-5%. It works better with products such as Nanoliposomal Vitamin A Palmitate and Nanoliposomal Ceramides. Storage: Keep it away from light at a temperature below 25°C. 17 www.cd-bioparticles.net
Slide 18 - Clipos™ Nanoliposomal Lutein Catalog no: CDPR-0016 CAS number: 127-40-2 Clipos™ Nanoliposomal Lutein has a particle size of less than 30nm and enables the lutein to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Lutein is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Lutein is a good antioxidant that protects cells in human body from the damage of free radical. Lutein is good for vision health as it can resist sunlight, blue light in computer and cellphone screens, relieve eye fatigue, sore eyes, tears, myopia, and prevent eye diseases such as cataracts and maculopathy. Lutein also plays a role in filtering blue light and strong anti-oxidation for the skin, greatly avoiding the damage of light to skin cells and preventing various kinds of skin disease caused by intense light stimulation. Features: Clipos™ Nanoliposomal Lutein uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Lutein is stable to heat, pH, and cuts, so it is convenient to use. Clipos™ Nanoliposomal Lutein greatly enhances the stability and bioavailability of lutein. Clipos™ Nanoliposomal Lutein improves the stability and absorption of other actives in the product. Clipos™ Nanoliposomal Lutein is 100% water soluble and has a wide range of applications. Usage: Add under low temperature; recommended dosage: 1-5%. Storage: Keep away from light at a temperature below 25°C. 18 www.cd-bioparticles.net
Slide 19 - Clipos™ Nanoliposomal Salicylic Acid Catalog no: CDPR-0017 CAS number: 69-72-7 Clipos™ Nanoliposomal Salicylic Acid has a particle size of less than 30nm and enables the salicylic acid to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Salicylic Acid is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Salicylic acid has an excellent ability to clear acne, exfoliate, and clean pores with safety. Salicylic acid can also lighten pigment spots, shrink pores, remove fine wrinkles, and improve aging caused by sun exposure, thus becoming the new favor of skincare products. Features: Clipos™ Nanoliposomal Salicylic Acid uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Salicylic Acid is stable to heat, pH and shearing, so it is convenient to use. Clipos™ Nanoliposomal Salicylic Acid overcomes the original shortcomings of salicylic acid while maintaining the advantages and improves bioavailability. Clipos™ Nanoliposomal Salicylic Acid can improve the stability of other active matters in the product and facilitate absorption. Usage: Add it at room temperature. You may heat it to over 40°C to speed up the dissolution. Recommended dosage: 1-5%. Divalent or trivalent metal ions such as iron must be avoided in the system. Storage: Keep it away from light at a temperature below 25°C. 19 www.cd-bioparticles.net
Slide 20 - Clipos™ Nanoliposomal Retinaldehyde Catalog no: CDPR-0018 CAS number: 116-31-4 Clipos™ Nanoliposomal Retinaldehyde has a particle size of less than 30nm and enables the retinaldehyde to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Retinaldehyde is amphiphilic and suitable for both water- soluble and oil soluble system, allowing a wide range of uses. Retinaldehyde (RAL), also known as vitamin A aldehyde, is a derivative of retinol after oxidation. It can be used as a skin care product to produce a variety of effects such as anti-aging, skin rejuvenation, whitening, anti-wrinkle, acne, and keratin. It is an emerging high- efficiency natural active substance. Features: Clipos™ Nanoliposomal Retinaldehyde uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Retinaldehyde has good heat, pH and sheer stability and is easy to use. Clipos™ Nanoliposomal Retinaldehyde greatly enhances the stability and bioavailability of retinal. Clipos™ Nanoliposomal Retinaldehyde can improve the stability of other active matters in the product and facilitate absorption. Clipos™ Nanoliposomal Retinaldehyde is 100% water soluble and 100% oil soluble, allowing a wide range of uses. Usage: Add it at room temperature; recommended dosage: 1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should avoid direct exposure to sunlight (using opaque packaging). It is recommended to add UV absorber to day care products. Storage: Keep it away from light at a temperature below 25°C. 20 www.cd-bioparticles.net
Slide 21 - Clipos™ Nanoliposomal Sulfur Catalog no: CDPR-0019 CAS number: 7704-34-9 Clipos™ Nanoliposomal Sulfur with a particle size of less than 30 nm developed by Nano-transport system (NDS) has completely solved sulfur’s solubility problem, allowing it to be stably encapsulated in a nanocarrier, which can greatly increase its absorption efficiency and bioavailability. Sulfur has long been an effective drug for the treatment of various skin diseases. Sulfur is a sebum regulating agent that has triple effects on problem skin, namely antibacterial, anti- inflammatory and sebum regulating. Water-soluble and non-irritating to the skin, in cosmetics, it can regulate the secretion function of sebaceous glands, and facilitate skin whitening. It is also effective in anti-bacteria, reducing the appearance of whelk, acne and dandruff. Features Clipos™ Nanoliposomal Sulfur uses FDA GRAS grade materials for safety. Clipos™ Nanoliposomal Sulfur has good heat, pH and shear stability and is easy to use. Clipos™ Nanoliposomal Sulfur improves the stability and absorption of other actives in the product. Clipos™ Nanoliposomal Sulfur is 100% water soluble and 100% oil soluble (amphiphilic) for a wide range of applications. Usage: Add at room temperature, heat it to above 40°C to speed up its dissolution. Recommended dosage: 1-3%. Better effect with products containing lipoic acid. Storage: Keep it below 25°C and away from light. 21 www.cd-bioparticles.net
Slide 22 - Clipos™ Nanoliposomal Ceramide Catalog no: CDPR-0020 CAS number: 100403-19-8 Clipos™ Nanoliposomal Ceramide has a particle size of less than 30nm and enables the ceramide to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal Ceramide is amphiphilic and suitable for both water-soluble and oil soluble system, allowing a wide range of uses. Ceramide is the most important component of the lipid barrier of the skin, and ceramide can repair the skin barrier function. The application of a skincare product containing ceramide for external use can achieve the purpose of preventing allergic skin diseases and the effect of suppressing melanin brown spots. Usage: Add it at an ordinary temperature; recommended dosage: 5-10%. Better effect with products such as yeast glucan liposome. Storage: Keep it away from light at a temperature below 25°C. 22 www.cd-bioparticles.net
Slide 23 - Phone:1-631-624-4882 Fax:1-631-938-8221 E-mail: info@cd-bioparticles.com 45-1 Ramsey Road, Shirley, NY 11967, USA www.cd-bioparticles.net Contact Us
 

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