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Slide 1 - Neural Stem Cells in Treating Diseases of the CNS Brooke McCarthy BME 281 Fall 2011
Slide 2 - Stem Cells Undifferentiated cells Types Cell division Induced to become specialized cells Physiologically Experimentally
Slide 3 - Neural Stem Cells Most fundamental cell of the nervous system Divides to create Neurons Astrocytes Oligodendroglia
Slide 4 - CNS Malignant glioblastomas Multiple sclerosis Niemann-Pick’s disease Current treatments
Slide 5 - NSC Therapy Inject Migrate Surround
Slide 6 - Results Multiple sclerosis Niemann-Pick’s disease Still too early
Slide 7 - Pros Best results Injection Either type of stem cell
Slide 8 - Problems Risks BTSC Mutation of NSC Largest part of brain tumors Resists treatments Genetic engineering
Slide 9 - Future Genetic engineering Cellular origins Other diseases
Slide 10 - Resources Achanta, P. "Gliomagenesis and the Use of Neural Stem Cells in Brain Tumor Treatment." Anticancer Agents Med Chem.(2010): 121-30. Pubmed. Web. 17 Sept. 2011. “Glioblastoma Multiforme.” Medscape. Web. 14 Sept. 2011. . Taupin, P. "Potential of Neural Stem Cells for the Treatment of Brain Tumors." Clinical Medicine: Oncology. (2008): 451-54. PubMed. Web. 17 Sept. 2011. “Stem Cell Information.” The National Institutes of Health. Web. 14 Sept. 2011. . “What are Stem Cells?” Medical News Today. Web. 14 Sept. 2011.