Download Recurrent Non small Cell Lung Cancer PowerPoint Presentation

Login   OR  Register

Share page


Home / Health & Wellness / Health & Wellness Presentations / Recurrent Non small Cell Lung Cancer PowerPoint Presentation

Recurrent Non small Cell Lung Cancer PowerPoint Presentation

onlinesearch By : onlinesearch

On : Feb 24, 2014

In : Health & Wellness

Embed :

Login / Signup - with account for

  • → Make favorite
  • → Flag as inappropriate
  • → Download Presentation
  • → Share Presentation
  • Slide 1 - The Need for 3rd-Line Therapy in Non-Small Cell Lung Cancer Frances A. Shepherd, MD Scott Taylor Chair in Lung Cancer ResearchPrincess Margaret Hospital Professor of Medicine, University of Toronto
  • Slide 2 - CRC-2 > 110,000 patientspotential candidates forsystemic therapy yearly Metastatic Resectable disease Locallyadvanced Most Patients With NSCLC Will Require Systemic Therapy ~80% relapse Shepherd. Semin Oncol. 1999. ~50% relapse
  • Slide 3 - CRC-3 Systemic Treatment for Advanced NSCLCChemotherapy — 1st-Line Modestly improves survival and symptoms Platinum-based regimens the standard Uncertain benefit in patients with PS 2 Toxicity an issue 1st- and 2nd-line
  • Slide 4 - CRC-4 2nd-Line Treatment for NSCLC Docetaxel is the only chemotherapy approved for NSCLC Response rate is low –— only 6% to 7% Demonstrated benefit in terms of survival and symptom control Toxicity is an issue
  • Slide 5 - CRC-5 3rd-Line Treatment for Advanced NSCLC For NSCLC, no standard definition for disease refractory to both platinum and docetaxel Clinical definition of 3rd-line: patients previously treated with a platinum and docetaxel who are not expected to benefit from additional treatment with same Single-agent chemotherapy now used for 3rd-line
  • Slide 6 - CRC-6 Massarelli et al. ASCO. 2002. Outcomes in NSCLC Patients From Startof 3rd- and 4th-Line Therapy Months after start of 3rd- or 4th-line therapy Survival probability 0 6 12 18 24 0.0 0.2 0.4 0.6 0.8 1.0 0.1 0.3 0.5 0.7 0.9 Objective response 2.3% (n = 1) Median survival 4.5 months 1-year survival 5% N = 43
  • Slide 7 - CRC-7 NSCLC Commonly Causes Disease-Related Symptoms Specific symptoms Shortness of breath Cough Tightness in the chest Difficulty breathing Poor Appetite and Weight loss Fatigue Type, severity, frequency depend on tumor location, disease burden, and growth rate
  • Slide 8 - CRC-8 Significance of Objective Responses in 3rd-Line Therapy of NSCLC Measure of antitumor activity Associated with symptom improvement Associated with better patient outcomes
  • Slide 9 - CRC-9 Disease-Related Symptoms in NSCLC When asked, 68% of patients with NSCLC who had already received platinum, stated they would choose chemotherapy compared to best supportive care if symptoms could be substantially reduced, even if survival was not prolonged Silvestri et al. 1998
  • Slide 10 - CRC-10 Goals of 3rd-Line Therapy in NSCLC Improve disease-related symptoms Improve performance status Treatment not an additional burden Enhanced patient control Holiday from IV therapy Less time away from home for treatment
  • Slide 11 - CRC-11 3rd-Line Therapy forNon-Small Cell Lung Cancer: an Unmet Need Increasing numbers of patients with NSCLC for 3rd-line therapy Most of these patients have significant disease-related symptoms No approved 3rd-line agents Standard chemotherapies a poor solution 3rd-line therapy for NSCLC represents an unmet medical need
Valuable Key Free PowerPoint Template

Valuable Key

Views : 826

Coffee Bean Free PowerPoint Template

Coffee Bean

Views : 281

Swans Free PowerPoint Template


Views : 437

Air Baloon Free PowerPoint Template

Air Baloon

Views : 916

Photography Free PowerPoint Template


Views : 444

Dollar Free PowerPoint Template


Views : 429

Room Interior Free PowerPoint Template

Room Interior

Views : 452

Tulips Free PowerPoint Template


Views : 224

Yoga Free PowerPoint Template


Views : 2354

Firefighters Free PowerPoint Template


Views : 1238

Mosquito Free PowerPoint Template


Views : 1867

Open Book Free PowerPoint Template

Open Book

Views : 914

Maple Leaf Free PowerPoint Template

Maple Leaf

Views : 473

Interior Free PowerPoint Template


Views : 520

Team Free PowerPoint Template


Views : 851

Step to Success Free PowerPoint Template

Step to Success

Views : 561

Statistics and Graph Free PowerPoint Template

Statistics and Graph

Views : 655

Domino Free PowerPoint Template


Views : 564

Gerbera Free PowerPoint Template


Views : 323

Gym Free PowerPoint Template


Views : 522

Description : Available Recurrent Non small Cell Lung Cancer powerpoint presentation for free download which is uploaded by search an active user in belonging ppt presentation Health & Wellness category.

Tags : Recurrent Non small Cell Lung Cancer

Shortcode : Get Shareable link