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Slide 1 - Robotic Total Mesorectal Excision Oscar I. Moreno Ponte MD
Slide 2 - Objectives 1.    Discuss overview of robotic surgery. 2.    Describe evolution of robotic surgery 3.    Discuss applicability of robotic surgery in colorectal surgery. 4.    Review oncological and clinical outcomes of laparoscopic mesorectal excision. 5.    Review oncological and clinical outcomes of robotic mesorectal excision.
Slide 3 - Robotic Surgery …”Developed to overcome the limitations of minimally Invasive Surgery and to enhance the capability of open surgery”…
Slide 4 - Chronological Events First Remote Cholecystectomy. The Lindbergh Operation Dr. Jacques Marescaux and Dr. Michel Gagner New York, September 2001.
Slide 5 - History of Robotic Surgery In 1985, PUMA 560 CT guided brain biopsy A robot with improved absolute positioning accuracy for CT guided stereotactic brain surgery. Kwoh, Y. Et all. Engng, Feb 1988, 35(2), 153–161.
Slide 6 - History of Robotic Surgery In 1988, The PROBOT PROBOT-A Computer Integrated Prostatectomy System Mei, Q. Et all. LNCS, 1996, Volume 1131/1996, 581-590
Slide 7 - History of Robotic Surgery In 1992, The ROBODOC The ROBODOC Clinical Trial: A Robotic Assistant for Total Hip Arthroplasty. Spencer. E.H. Et all Ort Nur, 1996, VOL 15; NUMBER 1,Pag 9-14
Slide 8 - History of Robotic Surgery In 1994, ZEUS Robotic Surgical System Robots Helping Surgeons: The da Vinci and ZEUS System By FDA
Slide 9 - History of Robotic Surgery In 2000, The da Vinci Surgical System Robots Helping Surgeons: The da Vinci and ZEUS System By FDA
Slide 10 - Chronological Events - 1997, Dr Tommaso Falcone, Cleveland Clinic; Successfully reconnection of fallopian tubes using ZEUS surgical system. - 1998, Dr Friedrich Wilhelm, Leipzig Heart Center; First Robotic Assisted heart bypass using da Vinci surgical System. - 1999, Dr. Randall Wolf and Dr. Robert Michler, The Ohio state university; First Robotic Assisted heart bypass in USA. - 2001, Dr. Jacques Marescaux and Dr. Michel Gagner; first remote cholecystectomy. - 2008, Dr. Mohan S. Gundeti, University of Chicago; First robotic pediatric neurogenic bladder reconstruction. - 2009, Dr. Stuart Geffner, Santa Barbara Medical Center, Ney Jersey; the first all-robotic-assisted Kidney transplant. - 2010, Dr. Borut Gersak, University Medical Centre Ljubljana; first robotic operation at the femoral vasculature
Slide 11 - Chronological Events First Fallopian Tube Reconstruction. Successful pregnancy 2 years after reconstruction. Dr Tommaso Falcone; Cleveland Clinic, July 1997.
Slide 12 - Chronological Events First Robotic Assisted heart bypass using da Vinci surgical System. Dr Friedrich Wilhelm; Leipzig Heart Center, Germany 1998
Slide 13 - Chronological Events First Robotic Assisted heart bypass in USA. Dr. Randall Wolf and Dr. Robert Michler The Ohio State University 1999
Slide 14 - Chronological Events 1999….World's first surgical robotics beating heart coronary artery bypass graft (CABG) was performed in Canada by Dr. Douglas Boyd and Dr. Reiza Rayman using the ZEUS surgical robot…. Same year…. the first closed-chest beating heart cardiac hybrid revascularization procedure is performed at the London Health Sciences Centre (London, Ontario)
Slide 15 - Chronological Events Robotic assisted Aortobifemoral bypass Dr Willem Wisselink, Vrije Universiteit Medical Center. Amsterdam, The Netherlands 2002
Slide 16 - Chronological Events First robotic pediatric neurogenic bladder reconstruction. Dr. Mohan S. Gundeti, University of Chicago 2008
Slide 17 - Chronological Events First all-robotic-assisted Kidney transplant. Dr. Stuart Geffner, Santa Barbara Medical Center, New Jersey 2009
Slide 18 - Robotic Surgery Application Otolaryngology—Head & Neck Surgery Gastrointestinal Surgery Cardiothoracic Surgery Cardiology and Electrophysiology Urology Gynecology Neurosurgery Orthopedic Pediatric
Slide 19 - Laparoscopic Surgery Standard of care for most benign and malignant colorectal disease. Less post-operative pain Better Cosmesis Early return of bowel function Shorter hospital stay Without sacrificing oncological clearance.
Slide 20 - Laparoscopic Surgery - Shortcomings of laparoscopic surgery Two dimensional view Dexterity of instruments within the abdominal space Fixed instruments tips with 4 degree of freedom Possible misalignment of hands and instruments
Slide 21 - Robotic Surgery The da Vinci Surgical system was developed to overcome shortcomings of laparoscopy….. Three dimensional imaging Stable camera and operating platform Articulating instruments with 7 degree of freedom Motion scaling and and tremor free movements Ergonomic Comfort
Slide 22 - Open Versus Laparoscopic Colorectal Surgery Cancer Treatment Reviews 2008 Vol 34, 498– 504
Slide 23 - Open versus Laparoscopic Colorectal Surgery
Slide 24 - Open versus Laparoscopic Colorectal Surgery Twelve trials More than 3346 patients No difference in recurrence rate No difference in Cancer related mortality
Slide 25 - Open versus Laparoscopic Colorectal Surgery
Slide 26 - Open versus Laparoscopic Colorectal Surgery ….” For any stage, 3 year survival and disease free interval are not worse in patients undergoing laparoscopic versus conventional open resection”……
Slide 27 - Laparoscopic Vs Open Surgery for rectal Cancer. COLOR II. A randomized clinical trial comparing laparoscopic and open surgery for rectal cancer. - International Clinical Trial - Primary end point: Loco-regional recurrence rate - Secondary end point: Disease free survival, post operative morbidity, quality of life and health economy analysis. “The results and safety of Laparoscopic Surgery in the treatment of rectal cancer remains unknown”
Slide 28 - Laparoscopic Rectal Surgery ….”Technical Complexity and long Learning curve can compromise oncologic Outcomes”…..
Slide 29 - Laparoscopic Rectal Surgery …”Ninety operation required to achieve oncological safety”….
Slide 30 - Robotic Rectal Surgery …” Stable view and precise movements make the Robot specially appropriate for manipulation of tissue in a closed and fixed space”… …” We believe that robotics could be relevant in the treatment of rectal cancer”….
Slide 31 - Robotic Colorectal Surgery Relatively new approach…. SURG ENDOSC 2002 Vol. 16, Number 8, 1187-1191
Slide 32 - Robotic Colorectal Surgery
Slide 33 - Robotic Colorectal Surgery Relatively new approach…. DIS COLON RECTUM 2002 Vol. 45, Number 12, 1689-1696
Slide 34 - Robotic Colorectal Surgery - Robotic Assisted Technique for the mobilization of the bowel - Three arm da Vinci System - Three-trocar Technique - Division of the Mesentery and Anastomosis performed with standard laparoscopic assisted technique. - Operative time 228-340 (180) - No Complication - Expected postoperative course
Slide 35 - Robotic Colorectal Surgery
Slide 36 - Robotic Rectal Surgery
Slide 37 - Robotic Rectal Surgery
Slide 38 - Robotic Rectal Surgery Operative Technique Hybrid Technique: Laparoscopic mobilization of the colon and Robotic TME Totally Robotic Anterior Resection A. Pagazzi et all; Surg Endosc 2006 Vol 20, 1521-1525 M. Hellam et all; Ann of Surg Onc 2007 Vol 14, 3168-3173
Slide 39 - Robotic Rectal Surgery
Slide 40 - Robotic Rectal Surgery LAR 80 (55.9%) CA 32 (22.4%) APR 31 (21.7%) Sphincter preservation achieve in 78.3 % Diverting Ileostomy 63% Operative time 297 min EBL 283 ml (0-6000 ml) Conversion to open 4.9% Ann Surg Oncol 2010 Vol 17:1614–1620
Slide 41 - Robotic Rectal Surgery Overall anastomotic leak 10.5% - Tumor Location >7 cm from the anal verge 9.3% - Lower tumors 16.4% Overall Pelvic Septic Complications abscess and leakages 16%
Slide 42 - Robotic Rectal Surgery Oncologic Outcomes Negative distal and circumferential margins 99.3% Mean number of harvested lymph nodes 14.1 Complete pathologic response 19.3% No Port site recurrence Total Recurrence 13 patients; Distant-only Mets 7.7% Local combined with distal Mets 1.5% No Local-only recurrence Disease free Survival at 3 years 76.6% Three year overall Survival rate 77% Ann Surg Oncol 2010 Vol 17:1614–1620
Slide 43 - Robotic Rectal Surgery “All circumferential and Distal resection margins were negative The medial number of harvested lymph nodes was 14.5”
Slide 44 - Robotic Rectal Surgery
Slide 45 - Robotic Vs Laparoscopic TME
Slide 46 - Robotic Vs Laparoscopic TME Ann Surg Oncol 2009 Vol 16:1480–1487
Slide 47 - Robotic Vs Laparoscopic TME Ann Surg Oncol 2009 Vol 16:1480–1487
Slide 48 - Robotic Vs Laparoscopic TME Ann Surg Oncol 2009 Vol 16:1480–1487
Slide 49 - Robotic Vs Laparoscopic TME Ann Surg Oncol 2009 Vol 16:1480–1487
Slide 50 - Robotic Vs Laparoscopic TME
Slide 51 - Robotic Vs Laparoscopic TME Surg Endosc 2010 Vol 24:2888–2894
Slide 52 - Robotic Vs Laparoscopic TME Surg Endosc 2010 Vol 24:2888–2894
Slide 53 - Robotic Vs Laparoscopic TME Surg Endosc 2010 Vol 24:2888–2894
Slide 54 - Robotic Vs Laparoscopic TME
Slide 55 - Robotic Vs Laparoscopic TME
Slide 56 - Robotic Vs Laparoscopic TME
Slide 57 - Robotic Vs Laparoscopic TME
Slide 58 - Robotic Vs Laparoscopic TME
Slide 59 - Conclusion The evolution of Robotic Surgery is limited due to small numbers of high volume centers The Robotic Technology will radically change general surgery and the fractionated subspecialties
Slide 60 - Conclusion The Robotic assisted surgery for benign and malignant disease of colon and rectum is safe and feasible Total Mesorectal Excision can be performed safely and effectively using the robotic system The clinical and oncological outcomes of the Robotic Total Mesorectal Excision can be compared with standard and open approach.
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