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Fibromyalgia Medical PowerPoint Presentation

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Fibromyalgia Medical Presentation Transcript

Slide 1 - Fibromyalgia R. John Looney, MD University of Rochester
Slide 2 - Fibromyalgia vs. Other Patients
Slide 3 - 1990 Criteria for Fibromyalgia Widespread pain 11 of 18 tender points
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Slide 5 - 2010 Diagnostic Criteria Widespread pain index (19 areas) Fatigue, waking unrefreshed, cognitive symptoms Present at similar level for 3 months Not otherwise explained
Slide 6 - Differential Degenerative disease: osteoarthritis, tendonitis, localized myofacial pain Inflammatory-immune disease: RA, SLE, Sjögren’s, Mixed Connective Tissue Disease. Scleroderma, Myositis, Undifferentiated Connective Tissue Disease, Vasculitis, Polymyalgia, Metabolic disease: hypo-/hyper-thyroid, high or low calcium, high or low potassium, liver disease, kidney disease Other: anemia, infection malignancy
Slide 7 - Myth – SLE Causes Pain “The most frequent cause of positive ANA and chronic pain is fibromyalgia! The failure to recognize that pain is NOT because of active SLE leads to much unnecessary glucocorticoid use and even inappropriate use of narcotics.” “Estimates for the prevalence of fibromyalgia among patients with SLE range from 10 to 30%.” A Clinician’s Pearls and Myths in Rheumatolody. Ed. John H.Stone
Slide 8 - Myth – Fatigue is a sign of active SLE “Fatigue is a major cause of reduced quality of life reported by SLE patients and is a significant contributor to disability. Acute fatigue often accompanies SLE flare , but this usually resolves along with the other features of active disease. However, for many patients with lupus, fatigue is a chronic symptom this is unresponsive to NSAIDs, glucocorticoids, and immunosuppressive medications. In these SLE patients, chronic fatigue is probably due to fibromyalgia.”
Slide 9 - SLE Flare - BILAG General Mucocutaneous Musculoskeletal Neurological Cardiovascular and respiratory Renal Vascular Hematologic
Slide 10 - Mild to Moderate Flare Mucocutaneous – discoid, photosensitive, profundus, cutaneous vasculitis, bullup lupus, nasopharyngeal ulcers Cardio/respiratory – pleurisy, pericarditis Musculoskeletal – arthritis General – fever
Slide 11 - Severe Flare Central nervous system lupus Vasculitis Nephritis Myositis Plt < 60,000 Hemolytic anemia Hgb < 7
Slide 12 - Flare of SLE vs. Flare of FM Pain in joints vs. tender points Evidence of inflammation Involvement of other systems Laboratory abnormalities Response to glucocorticoids, hydroxychloroquine, mycophenolate
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Slide 16 - SLE Flare - BILAG General Mucocutaneous Musculoskeletal Neurological Cardiovascular and respiratory Renal Vascular Hematologic
Slide 17 - Fibromyalgia = Central Sensitization
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