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Genetics PowerPoint Presentation

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Genetics Presentation Transcript

Slide 1 - Year 12 Biology Module 3: The Species Outcomes covered: 3.8, 3.9, 3.10, 3.11
Slide 2 - Autosomal Dominant Inheritance Dominant gene located on 1 of the autosomes Letters used are upper case ie BB or Bb Affected individuals have to carry at least 1 dominant gene (heterozygous or homozygous) Passed onto males and females Every person affected must have at least 1 parent with the trait Does not skip generations E.g. Huntington’s disease, Marfan syndrome
Slide 3 - Autosomal Dominant- Marfan syndrome
Slide 4 - Autosomal Recessive Inheritance The recessive gene is located on 1 of the autosomes Letters used are lower case ie bb Unaffected parents (heterozygous) can produce affected offspring (if they get both recessive genes ie homozygous) Inherited by both males and females Can skip generations If both parents have the trait then all offspring will also have the trait. The parents are both homozygous. E.g. cystic fibrosis, sickle cell anaemia, thalassemia
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Slide 7 - Autosomal Dominant/ Recessive Problems Cross a pure breeding, black coated guinea pig with a pure breeding, white coated guinea pig. Given that, in guinea pigs, black coat colour is dominant to white coat colour, determine the genotypes and phenotypes of the first and second generation offspring.
Slide 8 - Incomplete dominance In a heterozygous organism, neither gene is dominant, both genes are expressed equally Capital letters used for both alleles Snap dragons- red = RR, white= WW, pink = RW Cows- brown = BB, white= WW, roan=BW
Slide 9 - Incomplete dominance
Slide 10 - Incomplete dominance problems In Andalusian chickens, the black Andalusian character is incompletely dominant to the white-splashed Andalusian character. The heterozygous condition produces blue Andalusian chickens. Determine the genotypes and phenotypes of the F1 and F2 generations if a pure breeding, black Andalusian is crossed with a pure breeding, white-splashed Andalusian.
Slide 11 - Co- dominance Occurs when alternative alleles are present in the genotype and fully observed in the phenotype E.g. ABO blood grouping system, where a single gene locus features multiple alleles- IA, IB, and i. Individuals carrying alleles for both A and B express both in the phenotype AB.
Slide 12 - Co- dominance
Slide 13 - Sex linked inheritance Genes are carried on the sex chromosomes (X or Y) Sex-linked notation XBXB normal female XBXb carrier female XbXb affected female XBY normal male XbY affected male
Slide 14 - Sex linked inheritance Dominant Dominant gene on X chromosome Affected males pass to all daughters and none of their sons Genotype= XAY If the mother has an X- linked dominant trait and is homozygous (XAXA) all children will be affected If Mother heterozygous (XAXa) 50% chance of each child being affected E.g. dwarfism, rickets, brown teeth enamel.
Slide 15 - Sex linked dominant disorders
Slide 16 - Sex linked dominant problems The barred pattern of chicken feathers is inherited by a pair of sex linked genes, B for barred, b for no bars. If a non-barred female is mated to a barred male, a) What will the proportion and appearance of the offspring? What will be the appearance and proportion of the progeny produced by mating an Fl male with an Fl female?
Slide 17 - Sex linked Inheritance Recessive Gene located on the X chromosome More males than females affected (males inherit X from mother) Females can only inherit if the father is affected and mother is a carrier (hetero) or affected (homo) An affected female will pass the trait to all her sons Daughters will be carriers if father is not affected Males cannot be carriers (only have 1 X so either affected or not) Can skip generations E.g. colour blindness, haemophilia, Duchene muscular dystrophy
Slide 18 - Sex linked recessive problem Red-green colour blindness in men is caused by the presence of a sex-linked recessive gene c, whose normal allele is C. a) Can two colour blind parents produce a normal son? b) Can they produce a normal daughter? c) Can two normal parents produce a colourblind son or daughter? d) Can a normal daughter have a colourblind father or mother? e) Can a colourblind daughter have a normal father or mother?
Slide 19 - Sex linked Inheritance in Drosophila
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Slide 21 - General Pedigreerefer to NOB2 (new ed) pages 328-332
Slide 22 - Autosomal Dominant Pedigree Look for: Trait in every generation Once leaves the pedigree does not return Every person with the trait must have a parent with the trait Males and females equally affected
Slide 23 - Autosomal dominant pedigree
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Slide 25 - Autosomal Recessive Pedigree Look for: Skips in generation Unaffected parents can have affected children Affected person must be homozygous Males and females affected equally
Slide 26 - Autosomal recessive
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Slide 28 - Sex linked Dominant pedigrees Look for: More males being affected Affected males passing onto all daughter (dominant) and none of his sons Every affected person must have an affected parent
Slide 29 - Sex linked recessive pedigrees More ales being affected Affected female will pass onto all her sons Affected male will pass to daughters who will be a carrier (unless mother also affected) Unaffected father and carrier mother can produce affected sons
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Slide 31 - Sex linked recessive
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Slide 33 - Questions to complete Complete the following: Biochallenge pg 334, ques 2 Review ques pgs 335-338 Ques 6,7,8, 9, 10, 11, 12, 13, 14,
Slide 34 - This powerpoint was kindly donated to www.worldofteaching.com http://www.worldofteaching.com is home to over a thousand powerpoints submitted by teachers. This is a completely free site and requires no registration. Please visit and I hope it will help in your teaching.
 

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